Araştırma Çıktıları
PROJELER
- TÜBİTAK 1001-123Z892: “Synthesis of New Molecules Showing Quorum Sensing Inhibitory Properties and Their Use in Environmentally Friendly Hydrogel Paint System” (2024-2027).
- TÜBİTAK 1507-TEYDEP 7230061 “Industrial Paint Development Project with Environmentally Friendly Halloycite Clay Modified Encapsulation Technology for Water Contact Surfaces to be Used in Marine Vehicles” (2023-2024).
- TUBITAK 3005-122G101 Research Project “Culture and Technology Transfer in Ayasuluk/Efes in the Aydinoğullari-Early Ottoman Period: İsa Bey Bath Ceramics in the Light of Interdisciplinary Research” (2022-2024).
- TUBITAK 1001-117Z391 Research Project," Lead-Free New Generation Primer Explosive Design, Synthesis and Characterization” 15 October 2017-15 October 2021.
- TUBITAK 1001-117M165 Research Project, “Flame Aerosol Reactor Design, Control and Simulation for Continuous Production of Nanoparticles” 15 October 2017-2020.
- ATÜ-BAP A-1213-01 Research Project, “Electrochemical Investigations of Novel Bimetallic Antitumor Drugs with DNA” July 2013-2016.
- ATÜ-BAP 2011-01 Research Project, “Alginate Nanocarrier Systems for Controlled Drug Release, 2011.
- TUBITAK, COST 109T548 Research Project,"Synthesis electrochemical characterization and antioxidative anticancer effects of new platinum(II) complexes containing oxime derivative ligands”, 15/02/2007-15/12/2011.
- ATÜ-BAP 2009-03 Research Project, “Synthesis, electrochemical characterization and DNA binding activity of new platinum(II) complexes containing oxime derivative ligands” 1.11.2009-1.11.2011.
- ATÜ-BAP P2006/04 Research Project, “Synthesis, electrochemical characterization and antitumor activities new platinum blue complexes containing sulphur donor ligands”, 1.7.2006-30.6.2008.
- TUBITAK 101T037 Research Project, "Elecrochemical behaviours, Electronic absorption spectrum and electronic structure of binuclear rhodium complexes [Rh2(B-B)4L2](B-B=CH3CO2-, SO2-2, HPO2-)”, 01.09.2001-01.03.2003.
- TUBITAK 196T039 Research Project," Electrochemical behavior of metal complexes containing sulphur donor ligands”.
- TUBITAK 196T042 Research Project, “Ligand exchange kinetics of binuclear komplexes (M2(B-B)4L2)n-containing metal-metal bonds”, 01.09.1996-01.09.1998.
- TUBITAK 197T075 Research Project, “Preperation of carbon supported Pt+W and Pt+Mo catalyzers for methanol oxidation reactions, investigation of surface chemistry of Pt+W and Pt+Mo electrodes prepared by using nafion”, 01.08.1997-01.08.1999.
YÜKSEK LİSANS TEZLERİ
Tamamlanan:
- V. Selen Ünver, “Lead-Free New Generation Primer Explosive Design, Synthesis and Characterization”, (January 2018- June 2022) Supervisor.
- Hlyma Ali Ghit Mohamed Altahr, “Spectroelectrochemical investigations of Novel Platinum (II) Complexes Containing Bidentate Nitrogen and Sulphur Donor Ligands” . (Sept 2016- April 2018) Supervisor.
- Rehab Hesien, “Synthesis, Characterization, Electronic Structure and DNA Binding Abilities of Platinum(II) complexes containing 2,3-di(2-pyridyl)-quinoxaline ligand”, (Sept 2015- January 2018). Supervisor.
- Wadad Fadel, “Synthesis, Characterization, Electronic Structure and DNA Binding Abilities of Platinum(II) complexes containing 2,3-di(2-thienyl)-quinoxaline ligand”. (Sept 2015- January 2018). Supervisor.
- Marai Elkhajkhaj, “Synthesis, electrochemistry and spectroscopic behaviour of some palladium (II) complexes containing oxime ligands”. (March 2016-January 2018) Supervisor.
- Mohamed Musbah Abdusalam, “Synthesis and DNA Binding Ability of Novel Platinum (II) Complexes Containing Bidentate Nitrogen and Sulphur Donor Ligands”. (Sept 2014- January 2017). Supervisor.
- Safia Salem, “Synthesis and DNA interaction of the platinum blue complex containing 2-aminothiophenol”. (March 2015- January 2017). Supervisor.
- Asma Salem, “DNA Binding Ability of New Platinum (II) Complexes Containing 2,3-dihydro-5,6-di-2-pyridinyl Pyrazine Ligand”. (March 2015- June2017). Supervisor.
- Rema A. İbrahim, “Synthesis, characterization and binding behaviour of new Pt(II) complexes containing N-(pyridine-2-yl) methylene benzalamine with DNA, HSA and BSA using spectroscopic techniques”. (March 2015-June 2017). Supervisor.
- İsmail Erilhan: “The complex of 2-aminothiophenol ligand with platinum: A novel platinum blues containing sulfur donor ligand” (2007) Co-supervisor.
- Aytunç Göy: “Axial ligand kinetics of binuclear platinum complexes containing 2-mercaptopyridinate” (2007) Co-supervisor.
DOKTORA TEZLERİ:
Tamamlanan:
- Ahmed al Janabi, Development of platinum containing electro-catalyst supported on hybird support material for pem fuel cell”, MODES PROGRAM, (2019-January 2023) Co-supervisor.
- Hager Elbesti, Design, synthesis and biological activity of novel antitumor active platinum and copper based complexes containing quinoxaline ligands, CHEMISTRY PROGRAM, (2017- January 2022) Supervisor.
- Mahmoud Abduesslam, “Theoretical Investigation of Carbonyl Sulfide Capture by Organic Solvents”, MODES PROGRAM, (October 2018- June 2021) Supervisor.
- Magdi Buaisha, “Simulation and optimization algorithm to determine the design parameters of novel alternating activated sludge systems containing metal nanoparticle(s)”, MODES PROGRAM, (2015-2019) Co-supervisor.
- Rabia El Hag, “Novel palladium(II) and platinum(II) complexes containing dipyridy and dithiopyridyl ligands as potential anticancer drugs: Geometry optimization and spectroscopic properties of complexes by using DFT methods”, MODES PROGRAM, (2015-2018) Co-supervisor.
Devam Eden:
- Vahide Selen Yaman, “Design, synthesis and antiproliferative activity of metal complexes containing irinotecan derivatives”, CHEMISTRY PROGRAM, (2022- ) Supervisor.
- Cüneyt Demirer, “Design and preparation of antifouling paints containing new aminobenzothiazol derivatives and their metal complexes”, CHEMISTRY PROGRAM, (2021- ) Supervisor.
POST-DOC ÇALIŞMALARI
- Özlem Gümrah, “Development of lignin-based catalysts, electrosensors and chemosensors” (March 3th 2025- )
- Deniz Altınöz Erdoğan, “Synthesis electrochemical characterization and antioxidative anticancer effects of new platinum(II) complexes containing oxime derivative ligands” (2011-2012)
PATENTLER
|
Başvuru Numarası |
Başvuru Tarihi |
Başlık |
Kabul Tarihi |
1 |
EP17908720.0 (Germany) |
08.12.2017 |
New Generation Primary Explosive |
8.12.2021 (1105/3562797) |
2 |
EP17908564.2 (Germany) |
08.12.2017 |
Green Primary Explosive |
11.01.2022 (1105/3563111) |
3 |
TR 2015 17457 B |
30.12.2015 |
DNA hedefli mono ve heterodinükleer kompleksler |
21.01.2020 |
4 |
TR 2016 20025 B |
29.12.2016 |
Yeşil primer patlayıcı |
21.01.2022 |
5 |
TR 2016 19894 B |
28.12.2016 |
Yeni nesil primer patlayıcı |
21.01.2022 |
6 |
PCT/TR2023/050208 |
23.03.2023 |
Binuclear platinum(III) catalyst containing sulfate or hydrogen phosphate bridging ligand supported by carbon-based material for electrochemical power systems and method of preparation of this catalyst |
|
7 |
2022/003358 (Türk Patent) |
7.03.2022 |
Elekrokimyasal güç sistemleri için karbon temelli malzeme ile desteklenmiş sülfato veya hidrojenfosfato köprü ligandı içeren binükleer platin(III) katalizörü ve bu katalizörün hazırlanma yöntemi |
|
8 |
TR 2025/004726 |
18.4.2025 |
Deniz Taşitlarinda Kullanilmak Üzere Geliştirilen Bir Boya Ve Bunun Üretim Yöntemi |
|
9 |
PTC* |
Başvuru Aşamasında |
A Paint Developed For Use On Marine Vehicles And Its Production Method |
|
YAYINLAR
- Hager Sadek El–Beshti, Zuhal Gercek, Hakan Kayi, Yasemin Yıldızhan, Yüksel Çetin, Zelal Adigüzel, Gamze Güngör, Şeniz Özalp-Yaman, "Antiproliferative Activity of Platinum(II) and Copper(II) Complexes Containing Novel Biquinoxaline Ligands”, Metallomics, 16(2) (2024) mfae001-19. 10.1093/mtomcs/mfae001
- Hager Sadek El–Beshti, Yasemin Yıldızhan, Hakan Kayi, Yüksel Çetin, Zelal Adigüzel, Gamze Güngör, Zuhal Gercek, Şeniz Özalp-Yaman, "Anticancer Investigation of Platinum and Copper-Based Complexes Containing Quinoxaline Ligands", Journal of Molecular Structure 1250 (2022) 131928.
- M. Buaisha, Ş. Balku, Ş. Özalp Yaman, “Heavy metal inhibition on an alternating activated sludge system and its comparison to conventional methods: case study of Cu2+”, Water Science and Technology, 84(4), 892-904, 2021.
- M. Buaisha, Ş. Balku, Ş. Özalp Yaman, “Heavy Metal Removal Investigation in conventional Activated Sludge Systems”, Civil Engineering Journal, 6(3), 470-477, 2020. Doi:10.28991/cej-2020-03091484
- M. Buaisha, Ş. Balku, Ş. Özalp Yaman, “ANN-Assisted Forecasting of Adsorption Efficiency to Remove Heavy Metals”, Turkish Journal of Chemistry, 43, 1407-1424, 2019. Doi:10.3906/kim-1902-28
- R. El-Hag, M. M. Abdusalam, C.Acilan, Ş. Özalp Yaman, H. Kayi, “Radicalic cleavage pathway and DNA docking studies of novel chemotherapic platinum agent of 5,6-di-2-ithienyl-2,3-dihydropyrazine”, Polyhedron, 170, 25-33, 2019.
- Z. Adıgüzel, Ş. Özalp Yaman, G. Celik, C.Acilan,“A platinum-blue complex exerts its cytotoxic activity via DNA damage and induces apoptosis in cancer cells”, Chemical Biology & Drug Design, 90(2), 210-224, 2017.
- Adiguzel, Z.; Ozalp-Yaman, S.; Celik, G.; et al., “A platinum-blue complex exerts its cytotoxic activity via DNA damage and induces apoptosis in cancer cells” European Journal of Cancer, Volume: 61 Supplement: 1 Pages: S139-S139 Meeting Abstract: 624 Published: JUL 2016
- M. Buaisha, Ş. Balku, Ş. Özalp Yaman, “An optimum design for activated sludge systems” Athens Journal of Technology and Engineering, 3, 299-314, 2016.
- D. Altunoz Erdogan, F. Korkmaz, S.Özalp-Yaman, "Interaction of a Novel Platinum Drug with Bovine Serum Albumin: FTIR and UV-Vis Spectroscopy Analysis", New J.Chem., 39, 5676, 2015.
- D. Altunoz Erdogan, H. Kayi, S.Özalp-Yaman, “Spectroelectrochemical Investigation of Nuclease Active Pt(II) Complexes Containing Pyrrole Oxime”, J. Electrochimica Acta, 158, 333-341, 2015.
- D. Altunoz Erdogan, S.Ozalp-Yaman, “Novel Pt(II) complexes containing pyrrole oxime; synthesis, characterization and DNA binding studies”, J. of Mol. Structure, 1064, 50–57, 2014.
- O. Ozbek, S. Özalp-Yaman, I. Ozkan, A.M. Önal, H. Isci, “Spectroelectrochemical investigations of pyrimidine-2-thionato-bridged binuclear platinum(III) complexes” Polyhedron, 74, 122–128, 2014.
- H. Karaca, S. Sezer, S. Özalp-Yaman, C. Tanyeli, “Concise synthesis, electrochemistry and spectroelectrochemistry of phthalocyanines having triazole functionality”, Polyhedron, 72, 147–156, 2014.
- B.S. İşgör, Y.G. İsgör, Ş.Özalp Yaman “The role of metal coordination complexes in cytosolic cellular defense”, Pure Appl. Chem., Vol. 85, No. 2, pp. 365–375, 2013.
- Ş. Özalp-Yaman, Nergiz Ercil-Çağıltay, “How Can We Get Benefits of Computer-Based Testing in engineering Education?”, Computer Applications in Engineering Education, 21(2), 287-293, 2013.
- B.S. İşgör, Ş.Özalp Yaman, “Glutathion S-Transferase inhibitory of novel platinum complexes with ligands of oxime derivatves", FEBS Journal, 278 (1), 333-334 (2011).
- Şeniz Özalp-Yaman, Paul de Hoog, Palanisamy Uma Maheswari, Hélène Casellas, Amalija Golobič, Bojan Kozlevčar, Patrick Gamez and Jan Reedijk, Spectroelectrochemical Studies of Nuclease-Active Zinc(II) Coordination Compounds from the Ligands Hpyramol and Hpyrimol, Electrochimica Acta, 55 (2010), 8655-63.
- B.S. İşgör, Ş.Özalp Yaman, “A novel platinum blue complex containing sulfur-donor as a potential antitumor active drug", FEBS Journal, 276 (1), 314-315 (2009).
- Ş. Özalp-Yaman, P. de Hoog, G. Amadei, M. Pitié, P. Gamez, J. Dewelle, T. Mijatovic, B. Maunier, R. Kiss, J. Reedijk, Platinated copper(3-Clip-Phen) complexes as effective DNA-cleaving and cytotoxic agents, Chem. Eur. J., 14 (11), 3418-3426 (2008).
- P.U. Maheswari, S. Banderas, Ş. Özalp-Yaman, P. de Hoog, H. Casellas, S. J. Teat, C. Massera, M. Lutz, A. L. Spek, G. P. Van Wezel, P. Gamez and J. Reedijk, Unique ligand based oxidative Cleavage by zinc(II) complexes of Hpyramol and Hpyrimol, Chem. Eur. J. , 13, 5213-5222 (2007).
- C .Boldron, Ş. Özalp-Yaman, P. Gamez, D.M.Tooke, A.L Spek, J. Reedijk, Selective copper(II)-mediated oxidative coupling of a nucleophilic reagent to the para-methyl group of 2,4,6-trimethylphenol, Dalton Trans., 3535-3541 (2005).
- Ş. Özalp-Yaman, M.Baştürkmen, D.Kısakürek, Simultaneous novel synthesis of conducting and non-conducting halogenated polymers by electroinitiation of (2,4,6-trichloro-or 2,6-dichlorophenolato)Ni(II) complexes, Polymer, 46, 6786-6796 (2005).
- Ş. Özalp-Yaman, V.T. Kasumov, A.M. Önal, Electrochemistry of nickel(II) complexes with N,N’-bis(3,5-di-tert-butylsalicylidine)polymethylenediamines, Polyhedron, 24, 1821-1828 (2005).
- V.T. Kasumov, Ş.Özalp-Yaman, E.Taş, Synthesis spectroscopy and electrochemical behaviour of Nickel (II) complexes with tetradentate schiff bases derived from 3,5-Bu2t-salcylaldehyde, Spectrochimica Acta Part A, 62(1-3), 716-720(2005).
- V.T. Kasumov, E.Taş, F.Köksal, Ş.Özalp-Yaman, Synthesis characterization, redox behaviour and hydrogenation catalytic activity of bis(N-aryl-3,5-But2-salicylaldimino)palladium(II) complexes, Polyhedron, 24, 319-325 (2005).
- Ş. Özalp Yaman, A. M. Önal, H. İşçi, Electrochemistry of Acetato-, Carbonato-, Sulphato- and Dihydrogendisulphato- Bridged Dirhodium(II) Complexes, Zeitschrif für Naturforschung, 58b, 563-570 (2003).
- Ş. Özalp Yaman, A.M. Önal, L. Türker, Electrochemical and quantum chemical studies on mitomycin and adriamycin, Journal of Molecular Structure, 654, 81-93 (2003).
- A.M.Önal, H.İşçi, Ş. Özalp Yaman, Low Temperature Spectroelectrochemistry of Tetraethylammoniumtris(ethylxahnthato) Nickalate(II) and Bis(ethylxhanthato)nickel(II), Inorg. Reaction Mechanisms, 4 (3-4), 133-139 (2002).
- Ş. Özalp Yaman, E.Esentürk, C.Kayran, A.M.Önal, Spectrochemical Investigation of Pentacarbonyl(pyrazine)metal(0) (Metal=Cr, Mo, W) Complexes of Group 6 Elements, Z. Naturforsch, 57b, 92-98 (2002).
- Ö.Dağ, Ş. Özalp Yaman, A.M.Önal, H. İşçi, Spectro-electrochemistry of Potassium Ethylxhanthate, Bis(ethylxhanthato)nickel(II) and Tetraethylammoniumtris(ethylxhantato) nickelate(II), J. Chem. Soc., Dalton Transaction, 2819-2824 (2001).
- Ş. Özalp Yaman, A.M.Önal, H.İşçi, Spectro-Electrochemistry of Diethyldithiocarbomate Complexes of Ni(II), Pd(II) and Pt(II), Zeitschrif für Naturforschung, 56b, 202-208 (2001).