ECTS - Fundamental Principles of Tissue Engineering

Fundamental Principles of Tissue Engineering (MDES686) Course Detail

Course Name Course Code Season Lecture Hours Application Hours Lab Hours Credit ECTS
Fundamental Principles of Tissue Engineering MDES686 3 0 0 3 5
Pre-requisite Course(s)
Course Language English
Course Type N/A
Course Level Natural & Applied Sciences Master's Degree
Mode of Delivery Face To Face
Learning and Teaching Strategies Lecture.
Course Coordinator
Course Lecturer(s)
Course Assistants
Course Objectives The correlation between the principles and methods of engineering and life sciences toward the fundamental understanding of structure function relationships in normal and pathological mammalian tissues and the development of biological substitutes to restore, maintain, or improve tissue functions will be given.
Course Learning Outcomes The students who succeeded in this course;
  • Students will be learned how to use their backgrounds (engineers, biologists, and so on) for the multidisciplinary areas. They will get experience about combining the engineering analysis methods and the biological interactions.
Course Content Cell-tissue concepts, cell-tissue culture basic principles, tissue engineering, biomaterials, systems, proteins, biomaterial surface interactions, tissue microenvironment, organ loss and regeneration.

Weekly Subjects and Releated Preparation Studies

Week Subjects Preparation
1 Cell-tissue concepts, structural properties, metabolic functions. Related pages of the sources
2 Cell-tissue fundamental properties, practical offers. Related pages of the sources
3 Tissue engineering, biomaterials, systems. Related pages of the sources
4 Proteins, biomaterials, surface interactions. Related pages of the sources
5 Cell-biomaterials interactions. Related pages of the sources
6 Organ lost and regeneration. Related pages of the sources
7 The role of mass transfer in tissue functions. Related pages of the sources
8 The effect of shear force for cell functions. Related pages of the sources
9 Tissue microenvironment. Related pages of the sources
10 The production of various tissues by using tissue engineering principles. Related pages of the sources
11 Implantation and the tissue reactions after implantation. Related pages of the sources
12 Bioreactors. Related pages of the sources
13 Preservation of tissues. Related pages of the sources
14 Gen therapy. Related pages of the sources
15 Design of biomaterials for tissue engineering. Related pages of the sources
16 Evaluation and the brief summary of the above topics. Related pages of the sources


Course Book 1. -
Other Sources 2. Principles of Tissue Engineering, Robert P. Lanza, Robert Langer, Joseph Vacanti, Academic Press, 4th ed., 2013.
3. Biomaterials, Intersection of Biology and Materials Science, J. S. Temenoff, A. G. Mikos, Pearson Prentice Hall, 2008.
4. Bioengineering Fundamentals, Ann Saterbak, Larry V. McIntire, Ka-Yiu San, Pearson Prentice Hall, 2007.

Evaluation System

Requirements Number Percentage of Grade
Attendance/Participation 1 5
Laboratory - -
Application - -
Field Work - -
Special Course Internship - -
Quizzes/Studio Critics - -
Homework Assignments 2 5
Presentation - -
Project 2 25
Report - -
Seminar - -
Midterms Exams/Midterms Jury 1 30
Final Exam/Final Jury 1 35
Toplam 7 100
Percentage of Semester Work 65
Percentage of Final Work 35
Total 100

Course Category

Core Courses X
Major Area Courses
Supportive Courses
Media and Managment Skills Courses
Transferable Skill Courses

The Relation Between Course Learning Competencies and Program Qualifications

# Program Qualifications / Competencies Level of Contribution
1 2 3 4 5
1 Ability to expand and get in-depth information with scientific researches in the field of mechanical engineering, evaluate information, review and implement.
2 Have comprehensive knowledge about current techniques and methods and their limitations in Mechanical engineering.
3 To complete and apply knowledge by using scientific methods using uncertain, limited or incomplete data; use information from different disciplines.
4 Being aware of the new and developing practices of Mechanical Engineering and being able to examine and learn when needed.
5 Ability to define and formulate problems related to Mechanical Engineering and develop methods for solving and apply innovative methods in solutions.
6 Ability to develop new and/or original ideas and methods; design complex systems or processes and develop innovative/alternative solutions in the designs.
7 Ability to design and apply theoretical, experimental and modeling based researches; analyze and solve complex problems encountered in this process.
8 Work effectively in disciplinary and multi-disciplinary teams, lead leadership in such teams and develop solution approaches in complex situations; work independently and take responsibility.
9 To establish oral and written communication by using a foreign language at least at the level of European Language Portfolio B2 General Level.
10 Ability to convey the process and results of their studies systematically and clearly in written and oral form in national and international environments.
11 To know the social, environmental, health, security, law dimensions, project management and business life applications of engineering applications and to be aware of the constraints of their engineering applications.
12 Ability to observe social, scientific and ethical values in the stages of data collection, interpretation and announcement and in all professional activities.

ECTS/Workload Table

Activities Number Duration (Hours) Total Workload
Course Hours (Including Exam Week: 16 x Total Hours) 16 3 48
Special Course Internship
Field Work
Study Hours Out of Class 16 2 32
Presentation/Seminar Prepration
Homework Assignments 2 15 30
Quizzes/Studio Critics
Prepration of Midterm Exams/Midterm Jury 2 8 16
Prepration of Final Exams/Final Jury 1 10 10
Total Workload 136