The Cell (MED103) Course Detail

Course Name Course Code Season Lecture Hours Application Hours Lab Hours Credit ECTS
The Cell MED103 4 1 2 7 0
Pre-requisite Course(s)
-
Course Language English
Course Type N/A
Course Level Bachelor’s Degree (First Cycle)
Mode of Delivery Distance, Face To Face
Learning and Teaching Strategies Lecture, Discussion, Drill and Practice.
Course Coordinator
Course Lecturer(s)
Course Assistants
Course Objectives To introduce basic biochemistry, genetics and microbiology in order to learn the normal structure, function and their pathological conditions. To be able to understand basic interaction techniques and medical applications.
Course Learning Outcomes The students who succeeded in this course;
  • Understands the laboratory safety rules.
  • Describes the basics of cell structure and cytoskeleton; the intracellular communication pathways.
  • Explains the structure and function of DNA and RNA that store genetic information and interprets the relation between them; DNA isolation from cell.
  • Describes the structures and functions of organelles found in cell.
  • Describes the physiological features of homeostasis and properties of body fluid compartments.
  • Explains the transport system of substances through cell membrane.
  • Explains the electrical electrical potential mechanisms and action potential in a neuron.
  • Understands the mechanism of protein synthesis including transcription, translation, posttrancriptional and posttranslational modifications and intracellular protein trafficking.
  • Lists the cell structures of microorganisms.
  • Understands the classification and metabolism of bacteria; bacterial genetics.
  • Explains the mechanisms of bacterial pathogenesis.
  • Describes the classification, structure and replication of viruses; viral pathogenesis.
  • Describes the structure of a cell under microscope.
  • Applies basic cultivation techniques.
  • Describes the structures, reactions of amino acids, peptides and proteins.
  • Classifies amino acids and enzymes.
  • Understands the principles of enzyme kinetics.
  • Understands the structures of hydrocarbons and chemical bonds.
  • Understands how to calculate normality, molarity and percent volumes of solutions.
  • Understands how to prepare buffer solutions and measure pH.
  • Describes the principles of bioenergetics.
  • Explains cellular response to stress and noxious stimuli.
  • Describes cellular injury and cell death.
  • Describes the drug and routes and mechanism of drug administration.
  • Distinguishes cell membrane, nucleus, cytoplasm and organelles with histochemical dyes.
  • Examines and explains the parts of the microscope.
  • Sorts cell skeleton components and indicates their differences.
Course Content The origin of the cells and evolution, basic cell structure, cellular organelles, intracellular structures, transition of drugs through the biological membrane, pharmacokinetics of drugs, amino acids, enzymes, carbohydrates, introduction to microbiology, bacteria, fungi, parasites, acute inflammation, biostatistical methods

Weekly Subjects and Releated Preparation Studies

Week Subjects Preparation
1 Introduction to Cell Committee Cell origin and evolution Basic cell structure Histology aspect of Cell membrane, cytoplasm and organelles Introduction to Physiological Sciences, Basic Physiological principles and homeostasis Body fluid compartments and properties Lab: Normal, molar, percent solutionsHistology aspect of Nucleus Structure and Functions of Plasma Membrane Transport of substances through the cell membrane -
2 Electrical Potentials of Cell Membrane in Neuron Model The cell structures of microorganisms Electrical Potentials of Cell Membrane in Neuron Model Bioenergetics Fluid hemodynamic disorders Bacterial classification, structure and metabolism Macromolecules that store genetic information Lab: pH mete Human genome organization Mechanisms of bacterial pathogenesis -
3 Electrical Excitability and Action Potential in Neuron Model TBL:Intercellular Signal Transduction DNA as Heredity Molecule and DNA replication Amino acid structures, classification and reactions -
4 Peptides and proteins Bacterial genetics Pharmacodynamics: Receptors and Concentration Introduction to microbiology laboratory Cytoskeleton RNA types and functions General principles of laboratory diagnosis In vitro cultivation of bacteria -
5 Transfer of information from DNA to Protein I (transcription and posttranscriptional modifications) Pharmacokinetics Lab: Fundamentals of microscopy Viral classification, viral structure and replication Molecular Aspects of Drug Action -
6 Transfer of information from DNA to Protein II (translation and posttranslational modifications) Intracellular protein trafficking Cellular response to stress and noxious stimuli Viral pathogenesis Discussion time: Cell organelles and their structure and functions Lab: Spectrophotometer Molecular diagnostic methods in microbiology Cellular injury and cell death Intracellular accumulations Amyloidosis Pathologic Calcification Cellular Injury & Death -
7 Exam preparation and General exam -

Sources

Course Book 2. Emery's Elements of Medical Genetics (15th Edition); Peter D. Turnpenny, Sian Ellard; Elsevier, Philadelphia, 2017.
3. Harper’s Illustrated Biochemistry (31st Edition); Robert K. Murray, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, Victor W. Rodwell, P. Anthony Weil McGrawHill-Lange, 2018
4. Jawetz, Melnick, & Adelberg's Medical Microbiology, 28e, McGraw-Hill Education, 2019.
5. Lippincott Illustrated Reviews: Biochemistry (Seventh Edition); Denise R. Ferrier; Lippincott Wilwims & Wilkins; Philadelphia, 2017.
6. Marks’ Basic Medical Biochemistry A Clinical Approach (5th Edition); Michael Lieberman, Alisa Peet; Wolters Kluwer, Philadelphia, 2018.
8. Basic & Clinical Pharmacology (13th Edition); Bertram G. Katzung,‎ Anthony J. Trevor; McGraw-Hill, 2015.
9. Robbins Basic Pathology (10th edition); 2018 [edited by] Vinay Kumar, Abul K. Abbas, Jon C. Aster
9. Thompson & Thompson Genetics in Medicine (8th Edition); Robert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard; ; Elsevier, Philadelphia, 2016.
10. Histology and Cell Biology: An Introduction to Pathology (4th Edition); Abraham Kierszenbaum Laura Tres, Elsevier Saunders, Philadelphia, 2015
10. Cell and Molecular Biology (2nd edition); Nalini Chandar, PhD, Susan Viselli, PhD, Lipincot Wiliams & Wilkins, 2019.
11. Molecular Cell Biology (8th edition); Harvey Lodish, W.H.Freeman & Co Ltd, 2016.
12. Molecular Biology of the Cell (6th edition); Bruce Alberts, W. W. Norton & Company, 2015.
13. Medical Microbiology (8th Edition); Murray, Rosenthal, Pfaller, 2016.
14. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases (9th Edition); Bennett, JE, Dolin R, Blaser MJ. Elsevier, 2019.
15. Lehninger Principles of Biochemistry (7th Edition), David L. Nelson, Michael M. Cox W H Freeman & Co, 2017.
16. Textbook of Biochemistry with Clinical Correlations (7th Edition); Thomas M. Devlin (Editor) John Wiley & Sons, 2011.
17. Integrative Medical Biochemistry: Examination and Board Review, 1st Edition Michael W. King, Mc Graw Hill

Evaluation System

Requirements Number Percentage of Grade
Attendance/Participation 15 2
Laboratory 7 28
Application - -
Field Work - -
Special Course Internship - -
Quizzes/Studio Critics - -
Homework Assignments - -
Presentation - -
Project - -
Report - -
Seminar - -
Midterms Exams/Midterms Jury - -
Final Exam/Final Jury 1 70
Toplam 23 100
Percentage of Semester Work 30
Percentage of Final Work 70
Total 100

Course Category

Core Courses X
Major Area Courses
Supportive Courses
Media and Managment Skills Courses
Transferable Skill Courses

The Relation Between Course Learning Competencies and Program Qualifications

# Program Qualifications / Competencies Level of Contribution
1 2 3 4 5
1 Integrates and utilizes the information, skills, and approaches obtained from basic, clinical, and medical sciences, behavioral sciences, and social sciences when offering healthcare services. X
2 Offers healthcare services to patients with a biopsychosocial approach where the sociodemographic and sociocultural backgrounds of these individuals are taken into consideration, focusing on the universal human values, ethical principles, and professional duties; without exercising discrimination on the basis of language, religion, race, or sex. X
3 Aims to protect, improve, and develop individual and public health when offering healthcare services. X
4 Performs the necessary studies in sustaining and improving health, taking into the individual, public, social, and environmental factors to affect it. X
5 Trains healthy individuals/ patients, their relatives, and other healthcare workers in healthcare upon determining the features, requirements, and expectations of their target audience. X
6 Exercises a safe, rational, and effective approach in the procedures of prevention, diagnosis, treatment, follow-up, and rehabilitation; while offering healthcare services. X
7 Implements interventional and/or non-interventional practices in a way that is safe and effective for patients during the procedures of diagnosis, treatment, follow-up, and rehabilitation. X
8 Offers healthcare services taking into account the health and safety of patients and employees. X
9 Takes the regional and global changes in physical and socioeconomic settings to affect health, as well as the changes in the individual features and behaviors of patients referring to them into account, while offering healthcare. X
10 Takes the good medical practices into account while performing their duties. X
11 Undertakes the tasks and duties within the framework of their professional ethical rules, as well as their legal rights and duties. X
12 Stands for the improvements in the manner in which healthcare services are offered, taking into account the concepts of social reliability and social duty, in an effort to protect and improve individual and public health. X
13 Evaluates the effects of health policies and healthcare practices on public health indicators, and, where required, amends their evaluation on the grounds of scientific and social needs; in an effort to help improve the quality of healthcare services. X
14 Leads their healthcare team while offering healthcare services, in a participative, and collaborative manner. X
15 Establishes positive relationships within their healthcare team; and where needed, easily adapts to various positions among their team. X
16 Exercises effective communication with patients, the relatives of patients, healthcare professionals, and groups from other professions, as well as institutions and organizations. X
17 Plans and conducts scientific studies on the society to which they serve, and use the results of these, or those from other studies, to benefit the society. X
18 Accesses the current literature on their profession, and evaluates them with a critical approach. X
19 Chooses the correct sources of learning to improve the healthcare services that they offer, and regulates their own learning process. X
20 Demonstrates the skills of obtaining and evaluating new information, integrating newer pieces of information with their current ones, as well as adapting to changing conditions throughout their professional life. X

ECTS/Workload Table

Activities Number Duration (Hours) Total Workload
Course Hours (Including Exam Week: 16 x Total Hours) 7 11 77
Laboratory 7 1 7
Application
Special Course Internship
Field Work
Study Hours Out of Class 7 8 56
Presentation/Seminar Prepration
Project
Report
Homework Assignments
Quizzes/Studio Critics
Prepration of Midterm Exams/Midterm Jury
Prepration of Final Exams/Final Jury 7 11 77
Total Workload 217